Research objects

Tissue

AFM (elasticity, malice cancer)

FT-IR (chemical composition, detection of necrosis, apoptosis, lipid peroxidation, DNA conformation changes)

µXFR, µPIXE, XANES, RIXS (chemical changes and elemental distribution)

Cell

AFM (topography and organells detection)

FTIR , nanoIR (chemical and structural composition, necrosis and apoptosis detection, lipid peroxidase, conformational changes of DNA)

Chromosome

nanoIR (eu- and heterochromatin localisation, chromatin role in the formation of chromosomal aberrations, influence of ionizing radiation and chemoterapeutic drugs)

PCC, RT-PCR (classical and molecular cytogenetics)

DNA

TERS (Raman nanospectroscopy enhanced on the AFM tip) (DNA damage induced by ionizing radiation - bond breaks, cross links, chemical changes)

AFM (conformational changes)

RIXS (chemical changes)